Our new Distinct+ tissue clearing approach is the one system that delipidates samples without having change in morphology and with minimum effect on structural integrity.

Megatome can be a vibrating microtome built to portion a broad range of samples, from organoids and biopsy samples to expanded rodent brains and intact human organs. With higher blade vibrating frequency and minimized blade deflection, Megatome allows large-throughput tissue sectioning with uniform floor profile, together with negligible tissue destruction and information loss.

Antibodies may well acquire months to diffuse by only some millimeters of tissue, which has a steep labeling gradient from area to Main.

Megatome is designed for accuracy: the blade vibrates at a higher frequency and bigger amplitude vary than other microtomes, and encompasses a one of a kind deflection Command system.

SE takes advantage of a rotational electric powered subject to disperse hugely electromobile molecules (for example antibodies or surfactant micelles) all through a porous sample with out damaging electrically billed constructions within the tissue. This allows two-four day clearing of intact organs,

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eFLASH is really a quick tissue labeling method that allows for uniform full-organ staining in 20 rounds of labeling.

The SmartSPIM light sheet microscope supplies unparalleled resolution and acquisition speed through intact tissue volumes, while its modular style and design permits you to enhance and personalize unique elements.

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Protect avoids the variability of hydrogel embedding and the megatomi.com information loss from PFA preservation, safeguarding specimens for various rounds of processing.

Leverage the Apparent+ tissue clearing technique, in addition to eFLASH and patented stochastic electrotransport systems, to fast clear and label entire organs. Essential highlights and capabilities involve:

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